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TREATMENT OF TOOTH DISCOLORATION ASSOCIATED WITH TRIPLE ANTIBIOTIC THERAPY: CASE REPORTS

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±è¿µÀç ( Kim Young-Jae ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
±èÁ¤¿í ( Kim Jung-Wook ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
Àå±âÅà( Jang Ki-Taeg ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
ÀÌ»óÈÆ ( Lee Sang-Hoon ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
±èÁ¾Ã¶ ( Kim Chong-Chul ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
ÇѼ¼Çö ( Hahn Se-Hyun ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
ÇöÈ«±Ù ( Hyun Hong-Keun ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç

Abstract

±«»çµÈ ¹Ì¼º¼÷¿µ±¸Ä¡ÀÇ Ä¡¼öÄ¡·á¿¡ À־ Ä¡¼öÀÇ ÀçÇ÷°üÈ­¸¦ ÅëÇØ Ä¡±Ù´Ü ¹ßÀ° ¹× Ä¡±ÙÇü¼ºÀ» Áö¼ÓÇÏ·Á´Â °³³äÀÌ ¼Ò°³µÊÀ¸·Î½á ÇöÀç ¹Ì¼º¼÷¿µ±¸Ä¡ÀÇ Ä¡¼öÄ¡·áÀÇ ´ë¾ÈÀ¸·Î Á¦½ÃµÇ°í ÀÖ´Ù. ÀÌ·¯ÇÑ Ä¡±Ù´Ü ¿°ÁõÀ» °¡Áø ¹Ì¼º¼÷ ¿µ±¸Ä¡ÀÇ ÀçÇ÷°üÈ­¸¦ À§Çؼ­´Â °¡Àå Áß¿äÇÑ °ÍÀÌ ±Ù°ü³» °¨¿°µÈ ºÎºÐÀ» È®½ÇÈ÷ Á¦°ÅÇÏ´Â »ì±Õ(disinfection)ÀÌ´Ù. ±Ù°ü ³» °¨¿°Àº ¿©·¯ ¼¼±ÕÀÇ º¹ÇÕÀÛ¿ëÀ¸·Î ÀϾ±â ¶§¹®¿¡ öÀúÇÑ »ì±Õ¿¡ »ç¿ëµÇ´Â ¾àÁ¦ÀÇ Á¶ÇÕÀº ´Ù¾çÇÑ ¹üÀ§ÀÇ ±ÕÁÖ¸¦ ¸ðµÎ Á¦°Å °¡´ÉÇؾßÇÑ´Ù. Metronidazole(MN), ciprofloxacin(CF), minocycline(MC)ÀÇ ¼¼ °¡Áö º¹ÇÕÇ×»ýÁ¦°¡ ¾àÁ¦·Î »ç¿ëµÇ°í ÀÖÀ¸³ª ÀÌ º¹ÇÕÇ×»ýÁ¦ Àû¿ë ÈÄ Ä¡°üº¯»öÀ» ÀÏÀ¸Å°´Â »ç·Ê°¡ º¸°íµÇ°í ÀÖ´Ù. ÀÌ·¯ÇÑ Ä¡°üº¯»öÀº Ç×»ýÁ¦ÀÇ ¼ººÐ Áß MC¿¡ ÀÇÇÑ °ÍÀ¸·Î ¿©°ÜÁö°í ÀÖÀ¸¸ç, º» Áõ·Ê¿¡¼­´Â º¹ÇÕÇ×»ýÁ¦ Àû¿ë¿¡ ÀÇÇØ ¾ß±âµÈ Ä¡°üº¯»öÀÇ Áõ·Ê¸¦ ¼Ò°³ÇÏ°í À̸¦ Ç¥¹é¼ú·Î óġÇÏ¿© ÃÖÁ¾ ¼öº¹ÇÑ Áõ·Ê¸¦ º¸°íÇÏ¿´´Ù. º¹ÇÕÇ×»ýÁ¦ Àû¿ëÀ» ÅëÇØ ¹Ì¼º¼÷¿µ±¸Ä¡ÀÇ Ä¡¼öÄ¡·á¿¡ »õ·Î¿î Æз¯´ÙÀÓÀ» Á¦½ÃÇÑ °ÍÀº ºÐ¸íÇÏÁö¸¸ Ä¡°üº¯»ö µîÀÇ ºÎÀÛ¿ëÀÌ ÀÖÀ½À» ÀÎÁöÇÏ°í Ä¡°üº¯»öÀ» »çÀü¿¡ ¿¹¹æÇÏ°í ÃÖ¼ÒÈ­Çϱâ À§ÇØ ´Ù¾çÇÑ ¹æ¹ýÀÌ °­±¸µÇ¾î¾ß ÇÒ °ÍÀÌ´Ù.

The concept of revascularization of necrotic pulps regained interest and became an alternative conservative treatment option for young permanent teeth with immature roots. Revascularization of immature teeth with apical periodontitis depends mainly on disinfection of the canal. Since the infection of the root canal system is considered to be polymicrobial, a combination of drugs would be needed to treat the diverse flora. A triple antibiotic mixture of metronidazole, ciprofloxacin, and minocycline was used as an intracanal medicament. However, discoloration was developed after applying the triple antibiotic mixture. It is believed that the marked discoloration is related to the use of minocycline. The aim of this article was to present cases of coronal discoloration after triple antibiotic therapy in immature tooth and was treated with bleaching technique to control coronal discoloration. In conclusion, revascularization by using triple antibiotics promotes a paradigm shift in treating endodontically involved permanent teeth. However, we should understand that triple antibiotics containing minocycline induces tooth discoloration. Further research to prevent coronal discoloration should be investigated and suggested for the safe use of triple antibiotics.

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Triple antibiotics; Metronidazole; Minocycline; Ciprofloxacin; Crown discoloration; Bleaching

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